Douxo S3 Pyo Mousse, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, for Bacterial or Yeast Skin Infections, for Dogs, 5.1 fl. oz. (150mL)
$25.99
Price: $25.99
(as of Sep 28, 2025 22:54:37 UTC – Details)
Formulated with natural ingredients to help soothe, clean and strengthen the skin barrier. Moisturizes and detangles the fur to leave the coat soft and shiny. DOUXO is the 1 non-prescription topical brand used and recommended by U.S. veterinarians for treatment of dogs and cats with skin conditions.
Package Dimensions : 7.32 x 1.81 x 1.77 inches; 7.05 ounces
Item model number : D98310M
Date First Available : May 5, 2021
Manufacturer : Douxo S3
ASIN : B094783CJ9
Best Sellers Rank: #611 in Pet Supplies (See Top 100 in Pet Supplies) #60 in Dog Health Supplies
Customer Reviews: 4.6 4.6 out of 5 stars 4,002 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
#1 non-prescription topical brand used and recommended by U.S. veterinarians for dogs with skin conditions
Contains ophytrium, a purified natural ingredient that helps support the skin’s physical barrier for supple hydrated skin and helps soothe irritated skin
Free from soaps, sulfates, parabens, dyes and nanoparticlesDo not use DOUXO PYO Mousse on cats
Customers say
Customers find the fur cleaner effective, with one noting it works well between shampoos, and many reporting it helps with skin conditions and rashes. The product is easy to apply, has a pleasant smell, and effectively combats microbial odor. While some customers consider it worth the price, others feel there’s not enough product for the cost. Additionally, some customers report leakage issues with the product.
10 reviews for Douxo S3 Pyo Mousse, Contains 3% Chlorhexidine & 0.5% Ophytrium, Antiseptic & Hydrating, for Bacterial or Yeast Skin Infections, for Dogs, 5.1 fl. oz. (150mL)
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Mj –
Douxo Pyo 3 is lifesaver
Douxo Pyo 3 Mousse has been a money saver for my pitty. He’s plagued with an array of dermatitis type issues his entire life. Even as a pup, I remember the culprit being of a follicular/fungal deal. The douxo pyo was sent home from an expensive emergency vet visit 3 yrs back, but in a tub of wipes like Stridex pads. I was able to easily treat areas around my dog’s feet/toenails, lip folds, belly, etc. The mouse is awesome, it sinks in quickly, and it’s light in texture. There is no offensive or medicinal odor, which is a plus for sensitive areas being treated. This foam has a lighter lather, it feels clean without leaving a tack. My dog tends to flare up far less using the douxo pyo. The douxo line is a must for skin issues, I appreciate how quickly it seems to begin working. The treated areas began to heal faster and hair began growing back after spot use. Awesome stuff, try the douxo Calming Mousse if your dog gets the seasonal allergies like mine. It calms down hives, bug bites, hot spots, etc. I will continue purchasing this product.
Vi –
German Shepherd with Chronic Infections No More!
I do also use the shampoo from this brand but I believe the mousse is the product doing the heavy lifting.Took delivery May 14th, new photos and review from June 25th.My 3 year old GSD developed gnarly environmental allergies around 1 year old and it’s been a constant battle. His allergy medication is too expensive and not fully effective, so he only has it when I can afford it. Which these days, hasn’t been at all. Due to his constant scratching and chewing he would get skin infections over and over, I needed another way instead of paying $500 at the vet for an appointment and medication. He is 95lbs, so you can imagine the amount of medication he requires.I’ve tried a TON of different things. One example is the “Pet MD Chlorohexidine Wipes”, they are tiny, expensive, and ineffective. I used the entire container of 50 wipes over time and saw no differences in my dog. Medicated shampoos and conditioners, hot spot sprays, lotions, leave ins, nothing helped.As you can see in the photos my dog had grey, scaley skin in his armpit area, now, a month later it has completely cleared up. The insides of his forepaws were red, slimy, and bald from him chewing on himself. The photo doesn’t display it at its worst. His throat was completely bald and seeping a yellow goop, getting a photo of that was a little too uncomfortable for him but believe me when I tell you his neck is now dry and his fur is growing back. I am so grateful and will continue being subscribed to this product.I would recommend continued use even after any issues clear up if you have a dog with chronic skin issues out of fear that the infections will return. As for the smell, it does have a scent but I enjoy it.
Susan –
Kills yeast on skin within 48 hours
We have a large pyredoodle who suffers from seasonal yeast issues after several products this stopped the problem and we have a less itchy and happy pup. The smell is very pleasant and I will be trying the shampoo next season for sure
Demi –
Harsh, but works well
It works well, but it clearly is uncomfortable for my dog. He starts running around after application, as if it bothers him. Once it dries down, it does seem to help his feet though. It’s made the pads of his feet soft, which hasn’t been the case since he was a pup. But it is quite harsh. I recently ordered the pink one, and that one doesn’t seem to bother him like this one. It smells nice, and is as easy to apply as possible for a traumatized dog, that hates all the fuss over his feet and allergies. Poor bub.
jelliss –
Finally a Solution!
I spent $700 at the vet trying to figure out why my cat would lick a sore onto his lower belly. He would just continually lick a certain spot until it became a bigger and bigger open sore. The vet tried a vitamin b/steroid shot, blood work, topical hydrocortisone cream, even a biopsy with no luck. They told me it was “dermaritis”. We bought a cat onesie and cat cones to prevent him from locking the area. It would heal up completely, but once we took the car cone off, he would be right back at licking at irritating the hot spot. I then bought no-lick spray and a healing spray, and my cat would just lick through those. A friend whose dad is a retired vet recommended this product to me and it has actually done the trick! I rub it into my cat’s hot spot and he never attempts to lick it off and it soothes the troubled area so he licks it less. He still occasionally licks the hot spot, but when it gets red, I apply this mousse and the irritation goes back down.
liliane G –
Pour kes démangeaisons de bergers allemands
SG Tho –
Good for my dog skin
Carvalho Albuquerque –
It’s a really good product
Ros –
Came well packed. No leakage. Seems to relieve the itching in my dog’s paws.
Jess –
👍