Vetoquinol MPA Dermal-Soothe Anti Itch Pet Spray, 12oz
$28.99






Price: $28.99
(as of Jan 20, 2026 20:34:13 UTC – Details)
Product description

Vetoquinol, Looking After Pets Just Like Yours Since 1933
Vetoquinol is a family-owned company proudly devoted to looking after the health of animals. Since our beginnings in 1933, we’ve developed one of the largest research facilities in the world and employ over 100 world-class researchers.
We partner with veterinarians and animal health professionals across the globe to ensure we’re always at the forefront of pet care. We’re as passionate about your pet’s health as you are!

Vetoquinol Dermal-Soothe Spray for Pets with Normal, Dry, Itchy or Sensitive Skin
Micro Pearls Advantage Dermal-Soothe Anti-Itch Spray from Vetoquinol has been specially formulated to help soothe the irritation of dry, itchy or scaling skin in cats and dogs.
Gentle enough to be used regularly, even between shampoos, we’ve formulated our moisturizing spray without harsh steroids and antihistamines. Instead, we’ve added breakthrough ingredients developed to help soothe itching and deliver long-lasting hydration to the skin and coat.
We’ve also added Dermal-Soothe Shampoo, a conditioning anti-itch shampoo, and Dermal-Soothe Cream Rinse, a hydrating conditioner, to our Micro Pearls Advantage range, so that your pet can enjoy a life free from skin-related irritations.
Micro Pearls Advantage (MPA) Dermal-Soothe Horse, Cat and Dog Shampoo for Dry Itchy Skin

Itchy skin can be painful and irritating to any pet, and can cause a number of behaviors that make the problem worse such as biting, scratching and licking.
In many cases, itchiness is caused by dry, flaky skin that is lacking hydration. Many products only provide temporary relief, and are not designed to provide long-lasting moisture to both the skin and coat. We’ve designed a product line that works to address these root problems, delivering powerful, extended hydration to soothe your pet’s skin irritations.

Our anti-itch spray contains Pramoxine HCl, Novasome microvesicles, and Lactamide MEA, all breakthrough ingredients that work together in unity to achieve the final goal of a healthy, itch-free, moisturized and gleaming coat for your pet.
Pramoxine is used to temporarily relieve pain and itching.
Novasome microvesicles slowly deliver powerful hydration to the skin over time, providing long-lasting moisturization.
Lactamide MEA works to add and retain shine and moisture to the skin and coat.

We understand that as pet parents, it’s difficult to watch your loved ones suffer. Our ultimate goal is to provide relief to frustrated, irritated cats and dogs so that they are able to live a happier, healthier life.
By addressing the root cause of dry, flaky skin, we hope to give your pet the long-term relief they need to be their best self. Our powerful, breakthrough ingredients work together to create the formula that’s specifically designed to get the job done!

Dermal-Soothe Shampoo An anti-itch shampoo for dogs, cats and horses.Use regularly for clean, moisturized and hydrated skin and hair.With itch-relieving and moisturizing ingredients for long-lasting hydration.

Dermal-Soothe Cream Rinse An anti-itch conditioner for dogs, cats and horses.Use after shampooing with Dermal-Soothe Shampoo or other medicated shampoos to leave the coat soft and supple.With itch-relieving and moisturizing ingredients for long-lasting hydration and a colloidal oatmeal base to soothe dry, irritated skin.

Dermal-Soothe Spray An anti-itch spray for dogs and cats.Use after shampooing with Dermal-Soothe Shampoo or other medicated shampoos, or between baths to soothe itchy skin.With itch-relieving, moisturizing, and shine enhancing ingredients for long-lasting hydration and a lustrous coat.

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Customer Reviews
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4.7 out of 5 stars 611
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4.1 out of 5 stars 95
Price
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$16.49$16.49
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$28.99$28.99
Ideal for
Dogs, cats & horses Dogs & cats Dogs & cats Dogs, cats & horses Dogs, cats & horses Dogs & cats
Skin Type / Condition
Normal, dry & itchy Normal, dry & itchy Normal, dry & itchy Normal, dry, itchy & flaky Normal, dry, itchy & flaky Dry, itchy & flaky
Size(s)
16oz, 1 gallon 16oz, 1 gallon 16oz, 1 gallon 16oz 16oz 12oz
Use for
Deep Moisturization Itch relief, moisturization Skin softening, moisturization Itch relief, moisturization Itch relief, moisturization Itch relief, moisturization
Is Discontinued By Manufacturer : No
Product Dimensions : 8.25 x 1 x 2.25 inches; 14.2 Pounds
Item model number : 411528
Date First Available : November 11, 2006
Manufacturer : Vétoquinol USA
ASIN : B00AMEB7HY
Best Sellers Rank: #106,667 in Pet Supplies (See Top 100 in Pet Supplies) #138 in Cat Itch Remedies #590 in Dog Itch Remedies #1,214 in Horse Health Supplies
Customer Reviews: 4.1 4.1 out of 5 stars (95) var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
Give fast-acting itch relief to your pet, soothing irritation from an allergy, dry skin or hot spots
For both dogs and cats, our spray provides deep, penetrating, long-lasting hydration to dry skin
Leaves coat soft, supple and lustrous; your dog or cat with gleam with a natural, healthy shine
Soap-free formula won’t wash off other topical treatments; may be used with medicated shampoos
For best results, use with powerful itch-relieving Dermal-Soothe Shampoo & Dermal-Soothe Cream Rinse



A. Lewis –
Feline Skin relief
Went on line to find out what I could do for my very allergic tabby’s itchy skin which made him hypersensitive to touch. I saw an online vet in a video discussing how winter household heating systems dry out our pets skins just like it does to our skin. He was not promoting this product but I zoomed in to see what he was holding in his hand as he was combing product into a dog’s fur. I typed the name of the product into Amazon search and voila- they had it; I bought it; and the cat got instant relief. He didn’t even mind the spray or odor. I sprayed it on, massaged it into his fur and skin, and brushed him gently. Within 24 hours his itchiness and hypersensitivity were gone. His fur is shiny again and he smells so clean. I loved this product for my cat. The label says it works on dogs too.
TD –
Short term relief, but ahhhh
My poor little shitzu has become the itchiest little thing. I’ve switched to grain free, no chicken food, switched out her treats which alleviated some of it. I bought the Derm-Soothe shampoo and this spray and they are really helping alot. Remember that if you switch their food it may take 6 weeks to see any results, but she is better. This spray isn’t cheap, but to see her not scratching so much sure makes me happier. I recommend this product for your itchy little buddies, it worked for mine!
Sophie12345 –
Strong scent, cat hates it
My vet recommended this for my cat’s dry and flaky skin. I can’t speak to the effectives of this product, but the scent is so strong, my cat won’t let me get it near her. Note it’s not a bad scent, just super strong.
Tom77 –
My 🐶 thanks you 🥰
So glad I found this !! got it at veterinarian clinic and vet. said is safe to use for the gland issue odor too. Great size for the price. Great soft pleasant scent. Great quality!
Girl in the Mountains –
Great for in between bath’s
I haven’t noticed a huge change in the level of our dogs itching (they both have skin allergies in the fall, right before moulting) which was what I bought this for. Since I can’t rub skin soothing lotion on to huge fluffy Akita’s I hoped that this would be a sort of spray lotion of sort. There was a slight change in the itching but the thing I liked most is it makes them smell great and their coat feel so soft in between bath’s (Akita’s can’t have frequent bathes for it dry’s out there skin) that was the best thing about it to me.
Wayfarer –
Works like a charm for my cat’s flaky skin
I have a cat who has had very flaky skin, probably due to high indoor temperatures and dry air.I used to try to remove the flakes by grooming him, and also by once a season waterless shampooing,but neither of these things worked. Then I saw the recommendations for this product and decided totry it. I’m so glad I did! One application seemed to work miracles for my cat, and lasted for quite a longtime to remove the flakes and cut down on his dry and scruffy-looking skin. I’ve only needed to reapplythe product every month or so. The only negative thing I can think of is that at first the spray seems tohave a slightly too-sweet smell. But it leaves after a day or two and so is no problem.
PatchesNGabriel –
More Like Perfume Spray For Dogs
This Product is Highly Scented, too scented to be called an anti-Itch spray for dogs. You will not want to put this on a dog that is itching, have sensitive skin or any dog that needs to breathe. You may also not want to use it around humans who need to breath. We bought it for our yorkie with sensitive skin, it made his hair look and feel great. Beautiful shine, soft, easy to comb. After about hour we decided we needed to bath him. He couldn’t breathe, we couldn’t breathe. We ended up bathing him and giving him some allergy medication and a few family members including myself had to take allergy med. It was not a good experience. I was very disappointed with the product. I have no idea what the manufacturer was thinking when they decided to throw a bottle of perfume into an anti-itch product but I will not purchase it again.
S. Malbran –
Works
My elderly cat has FHS (Feline Hyperesthesia) who developed it after having a bad reaction to cat food and also having dry skin. We switched her food to blue buffalo, and after 2 weeks of her eating her knew food she was still having a small reaction. The vet suggested steroid shots, and after doing research, I decided I did not want this for her. The vet then advised us to try this. We’ve been using this for about a month now and she’s looking so much better and she isn’t scratching herself anymore. Steroids were my last resort and now I don’t have to put her through those horrible shots thanks to this product!
Tree 374 –
It arrived one week early and has a taped seal over the top. — I used this years ago on my Staffordshire. Her coat was very dry from sun in the Summer and the cold in the Winter (even with a good coat). I would spray some into my hands (which also warms it) and rub it on her coat and she just loved it. Coat became soft and moist (along with the skin). This was over a decade ago (she has since passed on). I now have 2 cats, and ordered it, hoping the formula hadn’t changed, and it hasn’t! One cat has a simple dry coat and the other has dandruff which is much worse than dander. One of my cats ran after he felt “wet” but then came back within seconds because it obviously felt good! and he let me do more. It has a sweet smell, dries quickly, and works wonders. It can be used as often as needed. I highly recommend it.